Showing titles in Genetics

Throughout history, people have sought to reduce suffering, eliminate disease and enhance desirable qualities in their children. In the Victorian era eugenics, a full-blooded attempt to impose control over unruly biology, began to grow among the powerful and quickly spread to dozens of countries around the world. But these ideas are not merely historical: today, with new gene editing techniques, conversations are happening about tinkering with the DNA of our unborn children to make them smarter, fitter, stronger.

By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only 24, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science's greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries.

In recent years, genetic testing has become easily available to consumers across the globe, making it relatively simple to find out where your ancestors came from. But what do these test results actually tell us about ourselves? In Ancestors, Pierre Zalloua, a leading authority on population genetics, argues that these test results have led to a dangerous oversimplification of what one’s genetic heritage means. Genetic ancestry has become conflated with anthropological categories such as “origin,” “ethnicity,” and even “race” in spite of the complexities that underlie these concepts.

With so much variation that can be handed down genetically, for better or worse, the way we understand our biology holds huge importance for how we understand our world and one another, including the biggest questions of our day, such as social inequality. Eye-opening and profound, Adaptable is a revolutionary reappraisal of an overlooked science.

Perched on the exterior of our delicate and intricate bodies, the skin is our largest and fastest growing organ. We see it, touch it and live in it every day. It's a habitat for a mesmerisingly complex world of micro-organisms, its physical functions are vital to our health and indeed our survival, and it's crucial to our sense of identity. Yet how much do we really know about it? Through the lenses of science, sociology and history, Dr Monty Lyman leads us on a journey through the comedy, tragedy and exquisite humanity of our most underrated and overlooked organ.

A preeminent geneticist hunts the Neanderthal genome to answer the biggest question of them all: what does it mean to be human? What can we learn from the genes of our closest evolutionary relatives? Neanderthal Man tells the story of geneticist Svante Pbo’s mission to answer that question, beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in his sequencing of the Neanderthal genome in 2009.

Each animal on the planet owes its existence to one very simple but crucial piece of evolutionary engineering: the egg. It's time to tell a new story of life on Earth.

The Ancestor's Tale is a pilgrimage back through time - a journey on which we meet up with fellow pilgrims as we and they converge on our common ancestors. Chimpanzees join us at about six million years in the past, gorillas at seven million years, orangutans at 14 million years, as we stride on together, a growing band. The journey provides the setting for a collection of some 40 tales.

Not since the atomic bomb has a technology so alarmed its inventors that they warned the world about its use. Not, that is, until the spring of 2015, when biologist Jennifer Doudna called for a worldwide moratorium on the use of the new gene-editing tool CRISPR - a revolutionary new technology that she helped create - to make heritable changes in human embryos.

Named one of the top books of 2009 by the Times Literary Supplement (London), this controversial and compelling audiobook from Dr. Stephen C. Meyer presents a convincing new case for intelligent design (ID) based on revolutionary discoveries in science and DNA. Along the way Meyer argues that Charles Darwin's theory of evolution as expounded in The Origin of Species did not, in fact, refute ID.

Racist pseudoscience may be on the rise, but science is no ally to racists. Instead science and history can be powerful allies against bigotry, granting us the clearest view of how people actually are, rather than how we judge them to be. How to Argue with a Racist dismantles outdated notions of race by illuminating what modern genetics can and can't tell us about human difference. It is a vital manifesto for a 21st-century understanding of human evolution and variation and a timely weapon against the misuse of science to justify racism.

With rapid advances in genomic technologies, genetic testing has become a key part of both clinical practice and research. Scientists are constantly discovering more about how genetics plays a role in health and disease, and healthcare providers are using this information to more accurately identify their patients' particular medical needs. Genetic information is also increasingly being used for a wide range of non-clinical purposes, such as exploring one's ancestry.

Geneticists like David Reich have made astounding advances in the field of genomics, which is proving to be as important as archaeology, linguistics, and written records as a means to understand our ancestry. In Who We Are and How We Got Here, Reich allows listeners to discover how the human genome provides not only all the information a human embryo needs to develop but also the hidden story of our species.

Epigenetics is the science of living DNA, charting the chemical pathways that spur DNA into action by turning genes on and off. While the Human Genome Project of the early 2000s was hailed as the key to understanding human heredity and disease, that historic effort was just the beginning. It has taken epigenetics to fill in the picture, explaining how the fixed code of our genome is implemented in countless living processes.

Since the discovery of DNA, scientists have believed that genes are fixed entities that cannot be changed by environment - we inherit them, pass them on to our children and take them with us when we die. Professor Tim Spector reveals how the latest genetic research and his own pioneering studies on epigenetics are rewriting everything we thought we knew about genes, identity and evolution.

Penguin presents the audiobook edition of Blueprint, written and read by Robert Plomin. The blueprint for our individuality lies in the 1 percent of DNA that differs between people. Our intellectual capacity, our introversion or extraversion, our vulnerability to mental illness, even whether we are a morning person - all of these aspects of our personality are profoundly shaped by our inherited DNA differences.

For over a century we saw Neanderthals as inferior to Homo Sapiens. After new discoveries, the pendulum swung the other way and they are generally seen as our relatives: not quite human, but similar enough, and still not equal. Now, thanks to an ongoing revolution in palaeoanthropology in which he has played a key part, Ludovic Slimak shows us that they are something altogether different - and they should be understood on their own terms rather than by comparing them to ourselves. As he reveals in this stunning book, the Neanderthals had their own history, their own rituals, their own customs.

What makes you the way you are - and what makes each of us different from everyone else? In Innate, leading neuroscientist and popular science blogger Kevin Mitchell traces human diversity and individual differences to their deepest level: in the wiring of our brains.

In this ground-breaking and entertaining exploration of athletic success, award-winning writer David Epstein gets to the heart of the great nature vs. nurture debate, and explodes myths about how and why humans excel. Along the way, Epstein exposes the flaws in the so-called 10,000-hour rule that states that rigorous practice from a young age is the only route to success.

Breakthroughs in genetics present us with a promise and a predicament. The promise is that we will soon be able to treat and prevent a host of debilitating diseases. The predicament is that our newfound genetic knowledge may enable us to manipulate our nature - to enhance our genetic traits and those of our children. Although most people find at least some forms of genetic engineering disquieting, it is not easy to articulate why.