Showing titles in History & Commentary

Through the moving stories of real people, neurologist Suzanne O'Sullivan explores the complex world of modern diagnosis, comparing the impact of a medical label to the pain of not knowing. With scientific authority and compassionate storytelling, she opens up new possibilities for how we might approach our health and our suffering.

Plagues upon the Earth is a monumental history of humans and their germs. Weaving together a grand narrative of global history with insights from cutting-edge genetics, Kyle Harper explains why humanity’s uniquely dangerous disease pool is rooted deep in our evolutionary past, and why its growth is accelerated by technological progress. He shows that the story of disease is entangled with the history of slavery, colonialism, and capitalism, and reveals the enduring effects of historical plagues all around us, in patterns of wealth, health, power, and inequality.

In the late 1600s, a distinguished English polymath, Robert Hooke, and an eccentric Dutch cloth-merchant, Antonie van Leeuwenhoek, look down their hand-made microscopes. What they see introduces a radical concept that sweeps through biology and medicine, touching virtually every aspect of the two sciences and altering both forever. It is the fact that complex living organisms are assemblages of tiny self-contained, self-regulating units. Our organs, our physiology, our selves—hearts, blood, brains—are built from these compartments. Hooke christens them "cells".

Interweaving a grand historical narrative with cutting-edge climate science and genetic discoveries, Kyle Harper traces how the fate of Rome was decided not just by emperors, soldiers, and barbarians but also by volcanic eruptions, solar cycles, climate instability, and devastating viruses and bacteria. He takes listeners from Rome's pinnacle in the second century, when the empire seemed an invincible superpower, to its unraveling by the seventh century, when Rome was politically fragmented and materially depleted.

Witness early, bloody, anaesthetic-free operations and first crude surgical instruments, trace the mapping of the circulatory system, follow the painstaking detective work that led to the decoding of the human genome and understand the role that potions, cures, therapies, herbal medicines and drugs have played in the human quest to tame and conquer disease, injury and death. An engrossing history and tale of drama and discovery that celebrates the milestones of medical history across generations and cultures.

Today, astonishing surgical breakthroughs are making limb transplants, face transplants, and a host of other previously undreamed-of operations possible. But getting here has not been a simple story of medical progress. In Blood and Guts, veteran science writer Richard Hollingham weaves a compelling narrative from the key moments in surgical history. We have a ringside seat in the operating theater of University College Hospital in London as world-renowned Victorian surgeon Robert Liston performs a remarkable amputation in 30 seconds - from first cut to final stitch.

Upon it's first publication 20 years ago, And The Band Played On was quickly recognized as a masterpiece of investigatve reporting. An international best seller, a nominee for the National Book Critics Circle Award, and made into a critically acclaimed movie, Shilts' expose revealed why AIDS was allowed to spread unchecked during the early 80's while the most trusted institutions ignored or denied the threat. One of the few true modern classics, it changed and framed how AIDS was discussed.

In mid-January 2020, scientists Ugur Sahin and Özlem Türeci learned of how a new virus that had emerged in Wuhan, China, was spreading. Recognising the threat at once, they dropped everything and committed themselves to developing a vaccine against the disease that would soon be known as COVID-19. No one believed it was possible. But by December, the revolutionary BioNTech-Pfizer mRNA inoculation became the first clinically approved COVID-19 vaccine. Soon it was being injected into the arms of millions, turning the tide on the deadliest pandemic in living memory.

The remarkable stories of the world's most famous body parts. All too often, historical figures feel distant and abstract; more myth and legend than real flesh and blood. These stories of bodies and its parts remind us that history's most-loved, and most-hated, were real breathing creatures who inhabited organs and limbs just like us - until they're cut off that is. Medical historian Dr Suzie Edge investigates over 40 cases of how we've used, abused, dug up, displayed, experimented on, and worshipped body parts.

Blending fascinating history with lacerating wit, The Mystery of the Exploding Teeth will take you on a tour of some of the funniest, strangest and most wince-inducing corners of medical history. This fascinating collection of historical curiosities explores some of the strangest cases that have perplexed doctors across the world.

When it comes to illness, sometimes the end is just the beginning. Recovery and convalescence are words that exist at the periphery of our lives - until we are forced to contend with what they really mean. Here, GP and writer Gavin Francis explores how - and why - we get better, revealing the many shapes recovery takes, its shifting history and the frequent failure of our modern lives to make adequate space for it.

The story of viruses and humanity is a story of fear and ignorance, of grief and heartbreak, and of great bravery and sacrifice. Michael Oldstone tells all these stories as he illuminates the history of the devastating diseases that have tormented humanity, focusing mostly on the most famous viruses. For this revised edition, Oldstone includes discussions of new viruses like SARS, bird flu, virally caused cancers, chronic wasting disease, and West Nile. Viruses, Plagues, and History paints a sweeping portrait of humanity's long-standing conflict with our unseen viral enemies.

Poppy tears, opium, heroin, fentanyl: humankind has been in thrall to the ‘Milk of Paradise’ for millennia. The latex of papaver somniferum is a bringer of sleep, of pleasurable lethargy, of relief from pain - and hugely addictive. A commodity without rival, it is renewable, easy to extract, transport and refine, and subject to an insatiable global demand. No other substance in the world is as simple to produce or as profitable. It is the basis of a gargantuan industry built upon a shady underworld, but ultimately it is a farm-gate material that lives many lives ....

We think of transplant surgery as one of the medical wonders of the modern world. But transplant surgery is as ancient as the pyramids, with a history more surprising than we might expect. Paul Craddock takes us on a journey - from 16th-century skin grafting to contemporary stem cell transplants - uncovering stories of operations performed by unexpected people in unexpected places.

For centuries, royal families have feared the gut-roiling, vomit-inducing agony of a little something added to their food or wine by an enemy. To avoid poison, they depended on tasters, unicorn horns and antidotes tested on condemned prisoners. The Royal Art of Poison is a hugely entertaining work of popular history that traces the use of poison as a political - and cosmetic - tool in the royal courts of Western Europe from the Middle Ages to the Kremlin today.

With poignant insight and humor, Frank Vertosick, Jr., MD, describes some of the greatest challenges of his career, including a six-week-old infant with a tumor in her brain, a young man struck down in his prime by paraplegia, and a minister with a .22-caliber bullet lodged in his skull. Told through intimate portraits of Vertosick's patients and unsparing-yet-fascinatingly detailed descriptions of surgical procedures, When the Air Hits Your Brain illuminates both the mysteries of the mind and the realities of the operating room.

The Tudor dynasty died out because there was no heir of Elizabeth I's body to succeed her. Henry VIII, despite his six marriages, had produced no legitimate son who would live into old age. Three of the reigning Tudors (Edward VI, Mary I, and Elizabeth I) died without heirs apparent, the most tragic case being that of Mary Tudor, who went through two recorded cases of phantom pregnancy. If it were not for physical frailty and the lack of reproductive health among the Tudors, the course of history might have been different.

With a death toll of between 50 and 100 million people and a global reach, the Spanish flu of 1918–1920 was the greatest human disaster. And yet, in our popular conception it exists largely as a footnote to World War I. Laura Spinney recounts the story of an overlooked pandemic, tracing it from Alaska to Brazil, from Persia to Spain and from South Africa to Odessa. She shows how the pandemic was shaped by the interaction of a virus and the humans it encountered, and how this devastating natural experiment put both the ingenuity and the vulnerability of humans to the test.

Some of the cruelest deeds of Japan's war in Asia did not occur on the battlefield, but in quiet, antiseptic medical wards in obscure parts of China. Far from front lines and prying eyes, Japanese doctors and their assistants subjected human guinea pigs to gruesome medical experiments in the name of science and Japan's wartime chemical and biological warfare research. Author Hal Gold draws upon a wealth of sources to construct a portrait of the Imperial Japanese Army's most notorious medical unit, giving an overview of its history and detailing its most shocking activities.

In 1918, the world faced the deadliest pandemic in human history. What can the story of the so-called Spanish Flu teach us about the fight against present day crises and how to prepare for future outbreaks? At the height of WWI, history's most lethal influenza virus erupted in an army camp in Kansas, moved east with American troops, then exploded, killing as many as 100 million people worldwide. It killed more people in 24 months than AIDS killed in 24 years, more in a year than the Black Death killed in a century.