• Iron overload aggravates MDS pathophysiology; long-term outcomes after TPO-RA treatment in ITP; new insights into APL treatment outcomes by age and risk

  • Jan 9 2025
  • Length: 17 mins
  • Podcast

Iron overload aggravates MDS pathophysiology; long-term outcomes after TPO-RA treatment in ITP; new insights into APL treatment outcomes by age and risk

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  • Summary

  • In this week's episode we'll learn about the role of iron in myelodysplastic syndromes, or MDS. After that: long-term treatment outcomes in immune thrombocytopenia from the STOPAGO study. Finally, new insights into APL treatment outcomes and prognostic factors from the large-scale Harmony APL project which used ATRA-Arsenic combination therapy.

    Featured Articles:

    • Genetic iron overload aggravates, and pharmacological iron restriction improves, MDS pathophysiology in a preclinical study
    • Long-term follow-up of the STOPAGO study
    • Acute promyelocytic leukemia: long-term outcomes from the HARMONY project
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