What do charlatans have to understand about human perception? Why are you so bad at recognizing a real penny among fakes? What did Eagleman have to do with the redesign of the Euro, and why did he campaign to the European Central Bank that all their bills should be blank with a single hologram in the middle? In this episode, explore the crossroads of perception and deception. Brief appearance from special guest Adam Savage.

Brains bear thoughts like a peach tree bears peaches. Even for meditators it's almost impossible to stop the firehose of words and images and ideas. But what in the world is a thought, physically? How can you hear a voice in your head when there's no one speaking in the outside world? And what does any of this have to do with a small marine animal who eats its own brain? Join Eagleman for this week's deep dive into our inner life.

How can we understand music's effect on human brains? Is music universal or does it rely on your experiences? How is music similar to a language? Can music be leveraged to help anxiety, dementia, or Parkinson's disease? What does any of this have to do with Stevie Wonder on the high hat, or the relationship between music and color? Join Eagleman with guest Daniel Levitin -- neuroscientist, musician, and author of This Is Your Brain on Music and I Heard There Was A Secret Chord.

Does our sense of self emerge from our brain's skill at lumping things into unchanging categories? What can we learn watching a caterpillar brain transition to a butterfly brain? Can we think of a memory as a pattern that stays alive and has its own life? Does an ant colony have a sense of self? Join Eagleman and biologist Michael Levin at Tufts – one of the most energetic and original thinkers in the field -- to dive into new territories of the self.

Every cell in your body changes, so why do you have a sense of continuity of the self – as though you're the same person you were a month ago? What does this have to do with the watercraft of the Greek demigod Theseus, or the End-of-History illusion, or why you go through so much trouble to make things comfortable for your future self, even though you don't know that person? And if there really were an afterlife, what age would your deity make everyone for living out their eternities? Join this week for a two-parter about the mysteries of selfhood.

Two certainties are death and taxes; a third is that people will work hard to avoid them both. But why is it so difficult to extend our lifespan? We know how to do it in worms and mice; why is it tricky in humans? Why do so few companies study longevity? What does the near future hold? What would it be like if everyone lived a much longer life? Join Eagleman this week with longevity expert Martin Borch Jensen to discuss the hopes and challenges of longevity science.

Why do brains dream, and why are dreams so bizarre? Why doesn't your clock work in your dreams? And even though you spend much of your working day looking at your cell phone and computer – why do they almost never make appearances in your dream content? Is dream content the same across cultures and across time? Are dreams experienced in black & white, or in color? Are dreams the strange love child of brain plasticity and the rotation of the planet? What is the relationship between schizophrenia and dreaming? In the future, will we be able to read out the content of somebody's dream? Join Eagleman this week to learn why and how we spend a fraction of our sleep time locked in different realities, swimming in plots which aren't real but which compel us entirely nonetheless.

What is depression? Why are brains able to slip into it? Is depression detectable in animals? Do animals have options beyond fight or flight? And what does any of this have to do with measuring depression medications in city water supplies, reward pathways in the brain, the prevalence of tuberculosis, and zapping the head with magnetic stimulation? Join today's episode with David Eagleman and his guest -- psychiatrist Jonathan Downar -- for a deep dive into the brain science behind depression and what new solutions are on the horizon.