• Your Brain on Insulin Resistance
    Jun 16 2025

    How is your brain affected by what you (over) eat? We examine a study which shows that even a brief period of overeating ultra-processed, high-calorie snacks can lead to lasting disruption in the brains insulin response & liver fat accumulation.

    Behind the Counter, shocking almost no one, science proves that weed makes you dumber.

    “What’s in the Bottle?,” you ask? Iron Advanced Essentials! Iron supports prenatal and cognitive health, as well as energy balance.

    ALL PRODUCTS: https://www.AskJoeDimatteo.com

    CONNECT:
    Products - https://askjoedimatteo.com/youtube
    Questions - questions@askjoedimatteo.com
    Facebook - https://facebook.com/askjoedimatteo
    Instagram - https://tinyurl.com/5n6kfwhs

    PODCAST:
    Apple Podcasts - https://tinyurl.com/GHShowApple
    Google Podcasts - https://tinyurl.com/GHShowGoogle
    Spotify - https://tinyurl.com/GHShowSpotify
    Rumble - https://rumble.com/user/GenerationHealth
    YouTube - https://tinyurl.com/57hxe6aj
    YouTube Clips - https://tinyurl.com/wzk69tbk

    Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

    CHAPTERS:
    00:31 - Show Intro
    00:39 - Behind the Counter
    03:26 - Discussion: Insulin & Obesity Risk
    03:49 - Brain insulin and obesity risk
    04:41 - How does insulin work?
    05:34 - Insulin sensitivity
    07:03 - Insulin and the brain
    08:38 - The study
    16:54 - What’s in the Bottle: Iron Advanced Essentials
    17:42 - What's in the update?
    18:50 - Why would you take this supplement?
    20:47 - How do we get iron from our diet?
    21:52 - Energy Balance
    22:38 - What's in Iron Advanced Essentials?
    23:55 - Dietary Intake of Iron
    25:39 - How do you become deficient in iron?
    28:54 - Dosage
    31:16 - Show Outro

    SHOW NOTES:
    1) Birth & Brain Growth (Article) - https://tinyurl.com/mrnz7cu2
    2) Cannabis Reduces Brain Activity (Article) - https://tinyurl.com/57cec8zh
    3) Rapid Dietary Effects on Brain Insulin and Obesity Risk (Article) - https://tinyurl.com/4dhs3vus
    4) Brain Insulin & High Calories (Study) - https://tinyurl.com/bdcrhk93
    5) Iron Advanced Essentials (Ask Joe DiMatteo) - https://tinyurl.com/trrc8smy
    6) Dietary Reference Intakes (NIH) - https://tinyurl.com/48tfycdf
    7) Iron metabolism in man (NIH) - https://tinyurl.com/3ypzyym7
    8) Physiology and molecular biology of iron absorption (NIH) - https://tinyurl.com/yydnztek
    9) Absorption of heme iron (NIH) - https://tinyurl.com/bdhkmbfc
    10) Bioavailability of minerals in legumes (NIH) - https://tinyurl.com/put2zfda
    11) Approaches to improve iron bioavailability from complementary foods (NIH) - https://tinyurl.com/bmejns2w
    12) Iron absorption from the whole diet in men (NIH) - https://tinyurl.com/4mykhexe
    13) Iron nutrition and absorption (NIH) - https://tinyurl.com/3avx6np6
    14) Iron supplementation in menstruating women with low ferritin (NIH) - https://tinyurl.com/4uv5mby7
    15) Prevent and Control Iron Deficiency in the U.S. (CDC) - https://tinyurl.com/23f3ncux

    DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

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    32 mins
  • Testosterone & TRT: Black Box Warning
    Jun 2 2025

    You don't see this very often! The FDA has REMOVED a "black box warning" from testosterone products used in TRT and other hormone therapies. The FDA uses box warnings when there is serious concern about a potential side effect. Seeing one removed is almost completely unheard of!

    Joey and Dante break down all the details on what's changing, the research behind it, and what it means for the millions of men using testosterone replacement therapy.

    ALL PRODUCTS: https://www.AskJoeDimatteo.com

    CONNECT:
    Products - https://askjoedimatteo.com/youtube
    Questions - questions@askjoedimatteo.com
    Facebook - https://facebook.com/askjoedimatteo
    Instagram - https://tinyurl.com/5n6kfwhs

    PODCAST:
    Apple Podcasts - https://tinyurl.com/GHShowApple
    Google Podcasts - https://tinyurl.com/GHShowGoogle
    Spotify - https://tinyurl.com/GHShowSpotify
    Rumble - https://rumble.com/user/GenerationHealth
    YouTube - https://tinyurl.com/57hxe6aj
    YouTube Clips - https://tinyurl.com/wzk69tbk

    Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

    CHAPTERS:
    00:25 - Show Intro
    01:26 - Unrelated Question
    05:26 - Discussion: FDA Changing labeling on TRT
    10:31 - How often does the FDA remove warnings?
    13:11 - More about the study
    16:50 - Dosing in the study
    22:14 - VA study
    26:22 - Show Outro

    SHOW NOTES:
    1) FDA Issues New Labeling (Article) - https://tinyurl.com/2nsu7rvy
    2) FDA Official Announcement - https://tinyurl.com/4xh5skz5
    3) Cardiovascular Safety of TRT (Study) - https://tinyurl.com/4xmaf7mt
    4) VA study of TRT & CV (Study) - https://tinyurl.com/46exs6da

    DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

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    28 mins
  • The Zero Calcium Score Danger
    May 12 2025

    When a doctor suspects plaque build-up in the arteries and vessels of a patient's heart, a non-invasive CT scan will often be used to detect the presence of calcium. That results are represented as a Calcium Score (Coronary Artery Calcium or CAC).

    So if the results come back and you have a low or even zero CAC, you're safe, right? Unfortunately, it's not that easy. Dante has the details based on a listener question.

    Joey gives us details on a product with a VERY specific use: Prenatal Complete with DHA! Creating life is not the time to use just any old prenatal, and Joey explains the details of why ours is worth the investment!

    ALL PRODUCTS: https://www.AskJoeDimatteo.com

    CONNECT:
    Products - https://askjoedimatteo.com/youtube
    Questions - questions@askjoedimatteo.com
    Facebook - https://facebook.com/askjoedimatteo
    Instagram - https://tinyurl.com/5n6kfwhs

    PODCAST:
    Apple Podcasts - https://tinyurl.com/GHShowApple
    Google Podcasts - https://tinyurl.com/GHShowGoogle
    Spotify - https://tinyurl.com/GHShowSpotify
    Rumble - https://rumble.com/user/GenerationHealth
    YouTube - https://tinyurl.com/57hxe6aj
    YouTube Clips - https://tinyurl.com/wzk69tbk

    Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

    SHOW NOTES:
    1) The Zero CAC Paradox (Study) - https://tinyurl.com/2pd476yp

    DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

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    38 mins
  • Beyond BMI: Redefining Obesity
    Apr 28 2025

    Is obesity a disease or does it lead to disease? Or is it merely a corollary with disease? What exactly is obesity? Where is the cutoff... and why?

    With questions like this raging in the medical community and popular-health world, the Lancet pulled together dozens of doctors and scientists to try and bring clarity based on the broadest and most well-established research. What they came up with is both critically important... and difficult to parse for the non-professional.

    This episode is extra long, but with obesity (and clinical obesity) comprising the single greatest challenge for Americans and the health of their families, we decided it was worth it!

    ALL PRODUCTS: https://www.AskJoeDimatteo.com

    CONNECT:
    Products - https://askjoedimatteo.com/youtube
    Questions - questions@askjoedimatteo.com
    Facebook - https://facebook.com/askjoedimatteo
    Instagram - https://tinyurl.com/5n6kfwhs

    PODCAST:
    Apple Podcasts - https://tinyurl.com/GHShowApple
    Google Podcasts - https://tinyurl.com/GHShowGoogle
    Spotify - https://tinyurl.com/GHShowSpotify
    Rumble - https://rumble.com/user/GenerationHealth
    YouTube - https://tinyurl.com/57hxe6aj
    YouTube Clips - https://tinyurl.com/wzk69tbk

    Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

    CHAPTERS:
    00:34 - Show Intro
    01:22 - Unrelated Question
    04:18 - Article: Is Obesity a disease state?
    06:04 - What was the definition of obesity?
    09:27 - What is the new definition of obesity?
    10:55 - How is it diagnosed?
    15:18 - What are the downsides of calling obesity a disease?
    19:37 - Pre-clinical vs. clinical obesity
    28:37 - FDA Indications for obesity medications
    35:23 - Public perception of obesity
    44:28 - Waist circumference
    48:10 - Body roundness index
    49:18 - Show Outro

    SHOW NOTES:
    1) Definition & Diagnosis of Obesity (Lancet) - https://tinyurl.com/y6bnkwjs
    2) Is obesity a disease? (Economist) - https://tinyurl.com/mrxrmtja

    DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

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    51 mins
  • Pregnancy and Forever Chemicals
    Apr 14 2025

    Joey digs into a new study linking prenatal exposure to FPAS via contaminated drinking water to an increase in childhood cancer. We unpack the research and discuss what women can do to protect their babies. This research has huge implications for young families!

    After that, Joey tells us exactly what's so exciting about one of our newest products, Ovarian Advanced Essentials. Designed to target women's hormone issues, Ovarian Advanced Essentials is built with the exact ratios of D-chiro Inositol and myoinositol that have been shown in research to the most help, particularly to women with PCOS. When hormones become unbalanced, the symptoms can be wide-ranging. Don't miss the chance to set things straight naturally!

    ALL PRODUCTS: https://www.AskJoeDimatteo.com

    CONNECT:
    Products - https://askjoedimatteo.com/youtube
    Questions - questions@askjoedimatteo.com
    Facebook - https://facebook.com/askjoedimatteo
    Instagram - https://tinyurl.com/5n6kfwhs

    PODCAST:
    Apple Podcasts - https://tinyurl.com/GHShowApple
    Google Podcasts - https://tinyurl.com/GHShowGoogle
    Spotify - https://tinyurl.com/GHShowSpotify
    Rumble - https://rumble.com/user/GenerationHealth
    YouTube - https://tinyurl.com/57hxe6aj
    YouTube Clips - https://tinyurl.com/wzk69tbk

    Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

    CHAPTERS:
    00:31 - Show Intro
    01:34 - Study: Prenatal exposure to PFAs in drinking water
    01:53 - What are PFAs?
    04:22 - What health risks to PFAs pose?
    09:31 - What do we do about PFAs?
    14:17 - WitB: Ovarian Advanced Essentials
    14:45 - What are ovaries?
    15:08 - What does OAE do?
    15:48 - Who is it for?
    16:46 - What is PCOS?
    20:37 - Study
    23:31 - What is in OAE?
    23:48 - Inositol
    26:11 - Other nutrients
    27:55 - Dosing
    28:49 - Show Outro

    SHOW NOTES:
    1) PFAS and Childhood Cancer - https://tinyurl.com/bddtfxu9
    2) PFAS & Cancer (Study) - https://tinyurl.com/3x2barmn
    3) Ovulation in PCOS (Study) - https://tinyurl.com/3pnn5jzx

    DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

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    30 mins
  • After Years of Ambien...
    Mar 31 2025

    We field a question from a listener about her husband’s Ambien use and dive into all things related to sleep aids. Watch for the good, bad, and the ugly of sleeping pills and other remedies for a better night’s sleep!

    Behind the counter, researchers further explain how Metformin scientifically helps Type 2 diabetes patients and does even more than that! Plus, does gut microbiome affect behavior? We examine a study that compares incarcerated women who are considered impulsive and violent and those who aren't.

    ALL PRODUCTS: https://www.AskJoeDimatteo.com

    CONNECT:
    Products - https://askjoedimatteo.com/youtube
    Questions - questions@askjoedimatteo.com
    Facebook - https://facebook.com/askjoedimatteo
    Instagram - https://tinyurl.com/5n6kfwhs

    PODCAST:
    Apple Podcasts - https://tinyurl.com/GHShowApple
    Google Podcasts - https://tinyurl.com/GHShowGoogle
    Spotify - https://tinyurl.com/GHShowSpotify
    Rumble - https://rumble.com/user/GenerationHealth
    YouTube - https://tinyurl.com/57hxe6aj
    YouTube Clips - https://tinyurl.com/wzk69tbk

    Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

    CHAPTERS:
    00:25 - Show Intro
    03:15 - Behind the Counter
    06:27 - Viewer Question: Ambien & Alternatives
    07:33 - Why is Ambien causing these issues?
    08:48 - What are peak plasma levels and “clearance?"
    15:27 - How is the alcohol affecting this situation?
    18:53 - Could diet be a contributing factor?
    19:57 - Why should someone take Ambien?
    22:59 - Is it typical to stay on Ambien this long?
    27:29 - Alternatives to using Ambien
    29:39 - Other pharmacological options
    31:23 - What does it look like to taper off Ambien?
    33:29 - Supplements for sleep
    35:03 - Show Outro

    SHOW NOTES:
    1) Unmasking Metformin (SciTechDaily) - https://tinyurl.com/5dhnb2zz
    2) Impulse Control (Karger) - https://tinyurl.com/6b5duhrv

    DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

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    36 mins
  • Pancake or Death?
    Mar 17 2025

    A widely publicized presentation (https://tinyurl.com/mup49t39) at the American Heart Association conference linked time-restricted eating (AKA intermittent fasting) to a 91% higher risk of cardiovascular death. If true, this has profound implications for anyone that skips breakfast!

    So... is it true?

    Also, Joey tells us exactly "What's in the Bottle" of our new Prostate Advanced Essentials! This precise blend of ingredients takes advantage of the latest research in how support the prostate. 90% of men will experience prostate problems at some point in life, so get ahead of it with proper support!

    ALL PRODUCTS: https://www.AskJoeDimatteo.com

    CONNECT:
    Products - https://askjoedimatteo.com/youtube
    Questions - questions@askjoedimatteo.com
    Facebook - https://facebook.com/askjoedimatteo
    Instagram - https://tinyurl.com/5n6kfwhs

    PODCAST:
    Apple Podcasts - https://tinyurl.com/GHShowApple
    Google Podcasts - https://tinyurl.com/GHShowGoogle
    Spotify - https://tinyurl.com/GHShowSpotify
    Rumble - https://rumble.com/user/GenerationHealth
    YouTube - https://tinyurl.com/57hxe6aj
    YouTube Clips - https://tinyurl.com/wzk69tbk

    Generation Health is a podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

    CHAPTERS:
    00:18 - Show Intro
    00:27 - Article: Time-Restricted Eating and Death
    03:12 - Takeaway from the study
    04:15 - How was this study set up?
    06:59 - Is this really about intermittent fasting?
    10:30 - Is intermittent fasting healthy?
    13:34 - Takeaways
    17:43 - What’s in the bottle: Prostate Advanced Essentials
    18:51 - What are the symptoms of BPH?
    20:47 - Side effects of BPH medications
    21:30 - What does this supplement do?
    22:55 - What's in Prostate Advanced Essentials?
    25:07 - What is Saw Palmetto?
    26:16 - What is Stinging Nettle?
    28:16 - Which minerals does PAE include?
    30:12 - Dosing
    30:56 - Show Outro


    SHOW NOTES:
    1) Time-Restricted Eating (Heart.org) - https://tinyurl.com/mup49t39

    DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

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    32 mins
  • Cancer, Alcohol & Warning Labels
    Feb 17 2025

    In the last days of the Biden administration, the Surgeon General called for cancer warnings on alcohol, similar to cigarette packs. Exactly what kinds of cancer risks does alcohol present, and how solid is this data? Will a new warning label actually make any difference?

    When a listener emails looking for advice on his high cholesterol, Dante draws clear distinctions between what is realistic for supplements to help and what requires the sledgehammer of medicine.

    ALL PRODUCTS: https://www.AskJoeDimatteo.com

    CONNECT:
    Products - https://askjoedimatteo.com/youtube
    Questions - questions@askjoedimatteo.com
    Facebook - https://facebook.com/askjoedimatteo
    Instagram - https://tinyurl.com/5n6kfwhs

    PODCAST:
    Apple Podcasts - https://tinyurl.com/GHShowApple
    Google Podcasts - https://tinyurl.com/GHShowGoogle
    Spotify - https://tinyurl.com/GHShowSpotify
    Rumble - https://rumble.com/user/GenerationHealth
    YouTube - https://tinyurl.com/57hxe6aj
    YouTube Clips - https://tinyurl.com/wzk69tbk

    Generation Health is a weekly podcast discussing cutting edge research and time tested best practices to help you live better, longer. Joey DiMatteo (PharmD, CCN), & Dante DiMatteo (PharmD) are the second generation in a family dedicated to helping educate listeners so they can make informed decisions about their own health. Incorporating their extensive knowledge in pharmaceuticals, nutrition, exercise, and supplementation, they love sharing their wisdom with anyone looking to improve their life!

    CHAPTERS:
    00:32 - Show Intro
    01:31 - Article: Link between alcohol and cancer
    04:49 - How does consuming alcohol lead to cancer?
    07:02 - What types of cancer can alcohol contribute to?
    07:40 - Will this warning label change behavior?
    17:51 - Raw numbers of the study
    19:09 - Is there any benefit to drinking alcohol?
    23:52 - Viewer Question: Should I take a statin?
    27:34 - Treatment for high LDL cholesterol
    30:01 - What are healthy levels of cholesterol?
    34:34 - Difference between total cholesterol and LDL
    35:59 - The other factors that contribute to cholesterol
    37:41 - Takeaway
    40:44 - Show Outro

    SHOW NOTES:
    1) Cancer Warnings on Alcohol (NYT) - https://tinyurl.com/ycka5prn
    2) Alcohol & Cancer Risk (HHS Site) - https://tinyurl.com/2jaf7ekv

    DISCLAIMER: This podcast is for general informational purposes only and does not constitute the practice of medicine, nursing, or other professional healthcare services, including the giving of medical advice. No doctor-patient relationship is formed. The use of this information and the materials linked to this podcast is at the user's own risk. The content on this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Listeners should NOT disregard or delay in obtaining medical advice for any medical condition they have, and they should seek the assistance of their healthcare professionals for any such conditions.

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    42 mins